Deploying six-dimensional movable antenna (6DMA) systems in Internet-of-Vehicles (IoV) scenarios can greatly enhance spectral efficiency. However, the high mobility of vehicles causes rapid spatio-temporal channel variations, posing a significant challenge to real-time 6DMA optimization. In this work, we pioneer the application of 6DMA in IoV and propose a low-complexity, instantaneous channel state information (CSI)-free dynamic configuration method. By integrating vehicle motion prediction with offline directional response priors, the proposed approach optimizes antenna positions and orientations at each reconfiguration epoch to maximize the average sum rate over a future time window. Simulation results in a typical urban intersection scenario demonstrate that the proposed 6DMA scheme significantly outperforms conventional fixed antenna arrays and simplified 6DMA baseline schemes in terms of total sum rate.